Title:
alpha-GALACTOSIDASE
Document Type and Number:
Japanese Patent JP2010263895
Kind Code:
A
Abstract:
To provide a new α-galactosidase for enzymatic removal of immunodominant monosaccharides on blood products and tissues.
There are provided: a new family of α3-glycosidase used for the enzymatic removal of type B antigens from blood group B and AB reactive blood products, and a Galili antigen from non-human animal tissues, to convert these substances to non-immunogenic cells and tissues suitable for transplantation; and a modified erythrocyte including type B erythrocyte or type AB erythrocyte devoid of immunodominant type B epitope and determined by serological typing.
COPYRIGHT: (C)2011,JPO&INPIT
Inventors:
CLAUSEN HENRICK
LIU QIYONG P
LIU QIYONG P
Application Number:
JP2010129803A
Publication Date:
November 25, 2010
Filing Date:
June 07, 2010
Export Citation:
Assignee:
VELICO MEDICAL INC
International Classes:
C12N15/09; A61K35/18; A61P7/00; C12N5/071; C12N5/078; C12N5/10; C12N9/40
Domestic Patent References:
| JP2005503808A | 2005-02-10 | |||
| JP2009516504A | 2009-04-23 |
Other References:
JPN6012011384; 'Ｔｒａｎｓｆｕｓｉｏｎ Ｃｌｉｎｉｑｕｅ ｅｔ Ｂｉｏｌｏｇｉｑｕｅ' ２００４， Ｖｏｌ．１１， ｐｐ．３３-３９
JPN6012011381; 'Ｓｃｉｅｎｃｅ' １９８２， Ｖｏｌ．２１５， ｐｐ．１６８-１７０
JPN6012011385; 'Ｎａｔｕｒｅ Ｂｉｏｔｅｃｈｎｏｌｏｇｙ' ２００７， Ｖｏｌ．２５， Ｎｏ．４， ｐｐ．４５４-４６４
JPN6012051698; 'Ｊｏｕｒｎａｌ ｏｆ Ｂｉｏｌｏｇｉｃａｌ Ｃｈｅｍｉｓｔｒｙ' ２００８， Ｖｏｌ．２８３， Ｎｏ．１３， ｐｐ．８５４５-８５５４
JPN6012051697; '"ＲｅｃＮａｍｅ： Ｆｕｌｌ＝Ａｌｐｈａ-１，３-ｇａｌａｃｔｏｓｉｄａｓｅ Ａ； ＡｌｔＮａｍｅ： Ｆｕｌｌ＝Ｅｘｏ-ａｌｐｈａ-ｇａｌａｃｔｏｓｉｄａｓｅ Ａ； ＡｌｔＮａｍｅ： Ｆｕｌｌ＝ＳａＧ' Ｑ８２６Ｃ５， ［ｏｎｌｉｎｅ］， Ｎａｔｉｏｎａｌ Ｃｅｎｔｅｒ ｆｏｒ Ｂｉｏｔｅｃｈｎｏｌｏｇｙ Ｉｎｆｏｒｍａｔｉｏｎ， ２００３年１０月１日掲載， ２０１２年９月２６日検
JPN6012051696; 'Ｔｉｓｓｕｅ Ｅｎｇｉｎｅｅｒｉｎｇ： Ｐａｒｔ Ａ' ２００９， Ｖｏｌ．１５， Ｎｏ．７， ｐｐ．１８０７-１８１９
JPN6012051697; '"ＲｅｃＮａｍｅ： Ｆｕｌｌ＝Ａｌｐｈａ-１，３-ｇａｌａｃｔｏｓｉｄａｓｅ Ａ； ＡｌｔＮａｍｅ： Ｆｕｌｌ＝Ｅｘｏ-ａｌｐｈａ-ｇａｌａｃｔｏｓｉｄａｓｅ Ａ； ＡｌｔＮａｍｅ： Ｆｕｌｌ＝ＳａＧ' Ｑ８２６Ｃ５， ［ｏｎｌｉｎｅ］， Ｎａｔｉｏｎａｌ Ｃｅｎｔｅｒ ｆｏｒ Ｂｉｏｔｅｃｈｎｏｌｏｇｙ Ｉｎｆｏｒｍａｔｉｏｎ， ２００３年１０月１日掲載， ２０１２年９月２６日検
JPN6012011381; 'Ｓｃｉｅｎｃｅ' １９８２， Ｖｏｌ．２１５， ｐｐ．１６８-１７０
JPN6012011385; 'Ｎａｔｕｒｅ Ｂｉｏｔｅｃｈｎｏｌｏｇｙ' ２００７， Ｖｏｌ．２５， Ｎｏ．４， ｐｐ．４５４-４６４
JPN6012051698; 'Ｊｏｕｒｎａｌ ｏｆ Ｂｉｏｌｏｇｉｃａｌ Ｃｈｅｍｉｓｔｒｙ' ２００８， Ｖｏｌ．２８３， Ｎｏ．１３， ｐｐ．８５４５-８５５４
JPN6012051697; '"ＲｅｃＮａｍｅ： Ｆｕｌｌ＝Ａｌｐｈａ-１，３-ｇａｌａｃｔｏｓｉｄａｓｅ Ａ； ＡｌｔＮａｍｅ： Ｆｕｌｌ＝Ｅｘｏ-ａｌｐｈａ-ｇａｌａｃｔｏｓｉｄａｓｅ Ａ； ＡｌｔＮａｍｅ： Ｆｕｌｌ＝ＳａＧ' Ｑ８２６Ｃ５， ［ｏｎｌｉｎｅ］， Ｎａｔｉｏｎａｌ Ｃｅｎｔｅｒ ｆｏｒ Ｂｉｏｔｅｃｈｎｏｌｏｇｙ Ｉｎｆｏｒｍａｔｉｏｎ， ２００３年１０月１日掲載， ２０１２年９月２６日検
JPN6012051696; 'Ｔｉｓｓｕｅ Ｅｎｇｉｎｅｅｒｉｎｇ： Ｐａｒｔ Ａ' ２００９， Ｖｏｌ．１５， Ｎｏ．７， ｐｐ．１８０７-１８１９
JPN6012051697; '"ＲｅｃＮａｍｅ： Ｆｕｌｌ＝Ａｌｐｈａ-１，３-ｇａｌａｃｔｏｓｉｄａｓｅ Ａ； ＡｌｔＮａｍｅ： Ｆｕｌｌ＝Ｅｘｏ-ａｌｐｈａ-ｇａｌａｃｔｏｓｉｄａｓｅ Ａ； ＡｌｔＮａｍｅ： Ｆｕｌｌ＝ＳａＧ' Ｑ８２６Ｃ５， ［ｏｎｌｉｎｅ］， Ｎａｔｉｏｎａｌ Ｃｅｎｔｅｒ ｆｏｒ Ｂｉｏｔｅｃｈｎｏｌｏｇｙ Ｉｎｆｏｒｍａｔｉｏｎ， ２００３年１０月１日掲載， ２０１２年９月２６日検
Attorney, Agent or Firm:
Hatsushi Shimizu
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Masato Ozeki
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Masato Ozeki
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