Title:
alpha-oxo acylamino caprolactam object
Document Type and Number:
Japanese Patent JP6226437
Kind Code:
B2
Abstract:
The purpose of the present invention is to provide a pharmaceutical composition that is useful for the treatment of diseases that are caused by an increase in bone resorption and that does not cause serious side effects even when used in combination with another drug. The present invention relates to: an ±-oxoacyl amino-caprolactam body that is represented by formula (I)
(in formula (I), X represents N or CH, Y represents O or CH 2 , and Z represents S or CH 2 ); and a bone resorption inhibitor containing the ±-oxoacyl amino-caprolactam.
Inventors:
Nobuo Kobayashi
Tsuneo Koji
Toshikuni Kunii
Mizuho Ishikawa
Morita Daisuke
Tsuneo Koji
Toshikuni Kunii
Mizuho Ishikawa
Morita Daisuke
Application Number:
JP2015522554A
Publication Date:
November 08, 2017
Filing Date:
June 13, 2014
Export Citation:
Assignee:
Seikagaku Corporation
International Classes:
C07D223/12; A61K31/55; A61P3/04; A61P3/12; A61P19/00; A61P19/02; A61P19/08; A61P19/10; A61P25/00; A61P29/00; A61P35/00; A61P35/04; A61P43/00; C07D405/12; C07D417/12
Domestic Patent References:
| JP2000204071A | ||||
| JP2012512864A | ||||
| JP2003527429A | ||||
| JP2007517810A |
Other References:
PAN, X. et al.,European Journal of Medicinal Chemistry,2010年,Vol.45, Iss.2,p.667-81
TULLY, D.C. et al.,Bioorganic & Medicinal Chemistry Letters,2006年,Vol.16, Iss.19,p.5112-7
TULLY, D.C. et al.,Bioorganic & Medicinal Chemistry Letters,2006年,Vol.16, Iss.19,p.5112-7
Attorney, Agent or Firm:
Norio Saeki
Yuko Saeki
Nakamura Tadashi Exhibition
Takuro Saeki
Naoko Ushiyama
Yuko Saeki
Nakamura Tadashi Exhibition
Takuro Saeki
Naoko Ushiyama
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