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Title:
An anti-KIR antibody, a tablet, and its use
Document Type and Number:
Japanese Patent JP6223771
Kind Code:
B2
Abstract:
A novel IgG4 isotype anti-KIR antibody, novel formulations of this and other IgG4 anti-KIR antibodies, and methods of using such formulations are provided. Also described are compositions, formulations, dosages, and administration regimens suitable for NK cell activation and therapeutic applications of anti-KIR antibodies, as well as kits comprising one or more anti-KIR antibodies with instructions for use in treating cancer.

Inventors:
Peter Andreas Nikolai Rumelt Woutmann
Ivan Svensen
Rosana Svenson
Rene Yurt Alifrangis
Rene Vie Or Go
Application Number:
JP2013213757A
Publication Date:
November 01, 2017
Filing Date:
October 11, 2013
Export Citation:
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Assignee:
Novo Nordisk Actiesel Scab
International Classes:
C12N15/09; A61K39/395; A61P35/00; A61P35/02; C07K16/28; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/08
Domestic Patent References:
JP9512705A
JP2005518802A
JP2005526956A
Foreign References:
WO2006003179A1
WO2005068503A1
Other References:
Molecular Immunology, Vol.30, pp.105-108 (1993)
Analytical Biochemistry, Vol.334, pp.81-88 (2004)
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Kenji Tomita



 
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