Title:
糖ペプチド及びペプチド性膜関連成分のコンジュゲートを含んでなる抗菌薬
Document Type and Number:
Japanese Patent JP4209673
Kind Code:
B2
Abstract:
The invention concerns agents with anti-bacterial activity and methods and intermediates for their production. The present invention further concerns the use of such agents for the treatment of bacterial infections in animals, including man. The agents are derivatives of vancomycin-type antibiotics, of structure: V-L-W-X; wherein V is a glycopeptide moiety which inhibits peptidoglycan biosynthesis in bacteria; L is a linking group; W is a peptidic membrane-associating element such as an element based on naturally-occurring animal or bacterial peptide antibiotics; and X is hydrogen or a membrane-insertive element.
Inventors:
Cooper, mash, alister
Betley, jason, richard
Betley, jason, richard
Application Number:
JP2002539370A
Publication Date:
January 14, 2009
Filing Date:
November 02, 2001
Export Citation:
Assignee:
CAMBRIDGE ENTERPRISE LIMITED
AdProTech Limited
AdProTech Limited
International Classes:
C07H17/00; C07K9/00; A61K31/7042; A61K47/48; A61P31/04; C07K7/08; C07K14/00; C07K14/195; C07K14/435; C07K14/46; C07K14/47; C07K19/00; A61K38/00
Foreign References:
| WO1998002454A1 | ||||
| WO1996030401A1 | ||||
| WO1998000153A1 |
Other References:
SCIENCE,1999年,Vol.284,p.507-511
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Ishii Teiji
Satoshi Fujita
Ishii Teiji