Antibodies that detoxify the human immunodeficiency virus and how to use them.

Title:

Antibodies that detoxify the human immunodeficiency virus and how to use them.

Document Type and Number:

Japanese Patent JP6323718

Kind Code:

B2

Abstract:

The invention provides broadly neutralizing antibodies directed to epitopes of Human Immunodeficiency Virus, or HIV. The invention further provides compositions containing HIV antibodies used for prophylaxis, and methods for diagnosis and treatment of HIV infection.

Inventors:

Shade, Johannes
Nuzenzweig, Michelle
Björkman, Pamela, Jay.
Diskin, Ron

Application Number:

JP2014511546A

Publication Date:

May 16, 2018

Filing Date:

May 17, 2012

Export Citation:

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Assignee:

THE ROCKEFELLER UNIVERSITY
California Institute of Technology

International Classes:

C12N15/09; A61K39/395; A61K45/00; A61P31/12; A61P31/18; C07K16/10; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/08

Foreign References:

US6465172

Other References:

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Database DDBJ/EMBL/GenBank [online],Accession No. AY452137,16-JUL-2004 uploaded,,DEFFINITION: Homo sapiens clone G14F7E5 immunoglobulin heavy chain mRNA, partial cds
Database DDBJ/EMBL/GenBank [online],Accession No. AY996339,02-MAY-2005 uploaded,,DEFFINITION: Homo sapiens clone MM25 immunoglobulin heavy chain variable region mRNA, partial cds
Biochem. Biophys. Res. Commun.,1989年 5月15日,Vol.160, No.3,p.1250-1256
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J. Immunol. Methods,2008年 1月 1日,Vol.329, No.1-2,p.112-124

Attorney, Agent or Firm:

Hatta International Patent Corporation

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