Title:
【発明の名称】嚢胞性繊維症治療用抗癌剤
Document Type and Number:
Japanese Patent JP2002502389
Kind Code:
A
Abstract:
The invention concerns a novel approach for treating cystic fibrosis using, in particular, anti-cancer chemotherapy. For the treatment of cystic fibrosis it proposes the use of at least one product which when administered to a patient brings about the expression or overexpression of an ABC carrier compound, in particular glutathione carrier. Preferably, the products used are anti-cancer products whose administration brings about the expression of MRP and/or MDR protein. The invention is also applicable to the treatment of rheumatoid polyarthritis or asthma. More specifically, the compounds are selected among cyclophosphamide, aclarubicin, doxorubicin, daunorubicin, epirubicin, idarubicin, zorubicin, pirabucin, colchicine, videsine, vinorelbine, vincristine, binblasine, azithromycin, erythromycin, ifosmamide, N-acetyl cysteine, N-acetyl lysine and/or a CFTR protein fragment comprising the NBF1 domain.
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Inventors:
Veronic, Steven
Gérard, Renoir
Jean-Eve, Larman
Jean-Philippe, Annuloux
Joel, Baltic
Sylvan, Blanke
Gérard, Renoir
Jean-Eve, Larman
Jean-Philippe, Annuloux
Joel, Baltic
Sylvan, Blanke
Application Number:
JP50033599A
Publication Date:
January 22, 2002
Filing Date:
May 28, 1998
Export Citation:
Assignee:
Centre National De La Recherche Scientifique (C.N.R.S)
International Classes:
A61K31/00; A61K31/131; A61K31/15; A61K31/165; A61K31/175; A61K31/255; A61K31/282; A61K31/36; A61K31/439; A61K31/475; A61K31/66; A61K31/664; A61K31/675; A61K31/70; A61K45/00; A61K31/704; A61K31/7052; A61K38/00; A61P11/00; A61P35/00; C07K14/47; G01N21/64; (IPC1-7): A61K45/00; A61K31/131; A61K31/15; A61K31/175; A61K31/255; A61K31/282; A61K31/36; A61K31/439; A61K31/664; A61K31/675; A61K31/704; A61K31/7052; A61K38/00; A61P11/00
Attorney, Agent or Firm:
Kazuo Sato (3 others)