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Title:
二重ジカルボン酸ジアミノプラチン錯体の抗腫瘍誘導体、その調製方法、それを含む薬剤組成物及びその誘導体の適用方法
Document Type and Number:
Japanese Patent JP3697210
Kind Code:
B2
Abstract:
The present invention relates to an antitumor derivative of double dicarboxylic acid diaminoplatin complex of formula (I): wherein R<1> and R<2> have the meanings defined in the specification, also relates to a process for preparation thereof, to an antitumor pharmaceutical composition containing the same, and further to application of the derivative in making antitumor pharmaceutics. The composition is a new generation of safe and effective antitumor drug, which has advantages such as low toxicity, broad antitumor spectrum, high antitumor activity, good solubility in water and fine stability in aqueous solution, selective killing of cancer cells without damaging normal cells, etc.

Inventors:
Yang Suttin
Yang Jen Yun
In in woo
Tsui Wei Chuan
Yang Jinri
Zhu Chencia
Application Number:
JP2001564191A
Publication Date:
September 21, 2005
Filing Date:
September 26, 2000
Export Citation:
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Assignee:
Yang Suttin
International Classes:
A61P35/00; A61K31/282; C07C61/04; C07F15/00; (IPC1-7): C07F15/00; A61K31/282; A61P35/00; C07C61/04
Other References:
Chem.-Biol.Interactions,1990年,73,p.337-351
Attorney, Agent or Firm:
Keisei Nishikawa
Atsuo Mori