A benzamide derivative for checking the activity of ABL1, ABL2, and BCR-ABL1

Japanese Patent JP6078639

B2

The present invention relates to compounds of formula (I): in which Y, Y1, R1, R2, R3 and R4 are defined in the Summary of the Invention; capable of inhibiting the activity of BCR-ABL1 and mutants thereof. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds in the treatment of cancers.

WO/2009/088070	(HETEROCYCLIC METHYL)AZOLYLMETHYLCYCLOPENTANOL DERIVATIVE AND INTERMEDIATE THEREOF, PROCESS FOR PRODUCTION OF THE DERIVATIVE, AND AGRICULTURAL OR HORTICULTURAL PREPARATION AND PROTECTIVE AGENT FOR INDUSTRIAL MATERIAL EACH COMPRISING THE DERIVATIVE
WO/2012/099736	IMPROVED PROCESS FOR PREPARATION OF HIGH MOLECULAR WEIGHT MOLYBDENUM SUCCINIMIDE COMPLEXES
WO/2023/120152	DIAMANTANE COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, AND ORGANIC ELECTROLUMINESCENCE ELEMENT

Dodd, Stephanie Kay
Furet, Pascal
Robert Martin, Grozfeld
Jones, Daryl Brynley
Manly paul
Martinic, Andreas
Pelle, Xavier Francois Andre
Salem, Baha
Shaper, joseph
Janke Wolfgang

JP2015512169A

February 08, 2017

May 09, 2013

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Novartis Age

C07D403/08; A61K9/14; A61K31/4155; A61K31/4439; A61K31/455; A61K31/496; A61K31/5025; A61K31/506; A61K31/661; A61K47/32; A61P35/02; A61P43/00; C07D213/82; C07D401/04; C07D401/14; C07D405/14; C07F9/6558

JP2005533827A
JP2015520158A
JP2015520157A
JP2015516460A

WO2008059023A1

Hiroshi Kobayashi
Norio Omori
Saori Oga
Uetake Yukiko
Yasuhito Suzuki

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