Title:
セロトニン5-HT6受容体の調節に応答する障害を治療するのに適したベンゼンスルホンアニリド化合物
Document Type and Number:
Japanese Patent JP2012525355
Kind Code:
A
Abstract:
The present invention relates to novel benzenesulfonanilide compounds of the formulae I and I′ and physiologically tolerated acid addition salts and the N-oxides thereof. The compounds possess valuable therapeutic properties and are particularly suitable, for treating diseases that respond to modulation of the serotonin 5-HT6 receptor. wherein n is 1 or 2; R1 is hydrogen or methyl and is positioned vicinal to the radical R1; R2 is hydrogen or methyl; R3 is C1-C3 alkyl; R4 is hydrogen, C1-C4 alkyl, cyclopropyl, C3-C4 cycloalkylmethyl or fluorinated C1-C4 alkyl; R5 is hydrogen, fluorine, chlorine, C1-C4 alkyl, fluorinated C1-C4 alkyl, C1-C4 alkoxy or fluorinated C1-C4 alkoxy; and R6 is hydrogen, fluorine or chlorine.
Inventors:
Haupt, Andreas
Pauluki, Frauke
Dresser, carla
Bitsuke, Karsten
Unger, Liliane
Relo, Anna-Lucia
Vespalov, Anton
Footsk, Barbara
Batsk Futushiyu, Gizela
Dell Tour, Jurgen
Jiang, Min
Pauluki, Frauke
Dresser, carla
Bitsuke, Karsten
Unger, Liliane
Relo, Anna-Lucia
Vespalov, Anton
Footsk, Barbara
Batsk Futushiyu, Gizela
Dell Tour, Jurgen
Jiang, Min
Application Number:
JP2012507762A
Publication Date:
October 22, 2012
Filing Date:
April 29, 2010
Export Citation:
Assignee:
ABBOTT LABORATORIES
International Classes:
C07D243/08; A61K31/495; A61K31/551; A61P3/04; A61P25/00; A61P25/18; A61P25/28; A61P25/30; C07D295/12
Attorney, Agent or Firm:
Kawaguchi International Patent Office
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