Title:
The benzonitrile derivative as a kinase inhibitor
Document Type and Number:
Japanese Patent JP6060163
Kind Code:
B2
Abstract:
Compounds of the formula I, in which R1, R2, X and Y have the meanings indicated in Claim 1, are inhibitors of TBK1 and IKKε and can be employed, inter alia, for the treatment of cancer and inflammatory diseases.
Inventors:
Holzemann, Gunther
Dolsh Dieter
Eggenbailler, Hans-Michael
Dolsh Dieter
Eggenbailler, Hans-Michael
Application Number:
JP2014528879A
Publication Date:
January 11, 2017
Filing Date:
August 13, 2012
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
C07D213/74; A61K31/4433; A61K31/4439; A61K31/444; A61K31/4545; A61K31/455; A61K31/496; A61K31/497; A61K31/501; A61K31/506; A61K31/519; A61K31/5377; A61P1/00; A61P3/00; A61P3/04; A61P3/10; A61P5/50; A61P7/00; A61P9/10; A61P11/00; A61P15/00; A61P17/02; A61P17/06; A61P19/02; A61P21/00; A61P25/00; A61P25/28; A61P27/02; A61P27/06; A61P29/00; A61P35/00; A61P37/02; A61P37/06; A61P43/00; C07D401/12; C07D401/14; C07D403/12; C07D405/14; C07D413/14; C07D417/14; C07D471/04; C07D491/107
Foreign References:
| WO2011046970A1 | ||||
| WO2012142329A1 |
Attorney, Agent or Firm:
Kiyoji Kuzuwa
Noriki Mitsuhashi
Noriki Mitsuhashi
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