Title:
ベンゾイミダゾール誘導体で置換されたベンゾピラン誘導体またはその製薬的に許容される塩、その製造方法及びそれを含む製薬組成物
Document Type and Number:
Japanese Patent JP4570624
Kind Code:
B2
Abstract:
The present invention relates to benzopyran derivatives substituted with a benzimidazole derivative, or pharmaceutically acceptable salts thereof, a preparation method of the same and pharmarceutical compositions containing them. Benzopyran derivatives substituted with a benzimidazole derivative, represented in Formula (1), have the function of protecting heart from ischemia-reperfusion without side effect like vasodilation, so that a pharmaceutical composition containing benzopyran derivatives substituted with a benzimidazole derivative or pharmaceutically acceptable salts thereof of the present invention as an effective ingredient can be effectively used for the protection of tissues influenced by ischemia-reperfusion, for example, for the protection of heart, nervous cells, brain, retinal cells, storage organs, etc. and for the treatment of diseases caused by ischemia-reperfusion.
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Inventors:
Rim Hong
Redon Ha
Kim Seung Ok
Yosun-Yoon
Ikyuyan
Listen Kyun
Sujehi
Kim nak john
One Sung Kyun
Kim Taemi
Libunho
Soho-won
Redon Ha
Kim Seung Ok
Yosun-Yoon
Ikyuyan
Listen Kyun
Sujehi
Kim nak john
One Sung Kyun
Kim Taemi
Libunho
Soho-won
Application Number:
JP2006532064A
Publication Date:
October 27, 2010
Filing Date:
May 28, 2004
Export Citation:
Assignee:
DONGBU HANNONG CHEMICAL CO.,LTD
International Classes:
C07D405/04; A61K31/4184; A61P7/02; A61P9/00; A61P9/04; A61P9/10; A61P43/00; C07D405/14; C07D493/10
Domestic Patent References:
| JP4243852A | ||||
| JP2003512367A |
Attorney, Agent or Firm:
Eiji Saegusa
Kakehi Yuro
Kenji Saito
Kakehi Yuro
Kenji Saito