Title:
ヒストンデアセチラーゼの新規な阻害剤としてのカルボニルアミノ誘導体
Document Type and Number:
Japanese Patent JP2005519950
Kind Code:
A
Abstract:
This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, R3, R4, R5, L, Q, X, Y and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
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Inventors:
Van Emmelen, Christoph
Beldonck, Marc Gustav Serene
Van Brandt, Sfuen Franciscus Anna
Bax, Leo Jacobs Joseph
Beldonck, Marc Gustav Serene
Van Brandt, Sfuen Franciscus Anna
Bax, Leo Jacobs Joseph
Application Number:
JP2003574617A
Publication Date:
July 07, 2005
Filing Date:
March 11, 2003
Export Citation:
Assignee:
JANSSEN PHARMACEUTICA NAAMLOZE VENNOOTSCHAP
International Classes:
C07D249/12; A61K31/40; A61K31/438; A61K31/4427; A61K31/4439; A61K31/444; A61K31/445; A61K31/4468; A61K31/451; A61K31/4545; A61K31/4709; A61K31/472; A61K31/4725; A61K31/495; A61K31/496; A61K31/497; A61K31/506; A61K31/517; A61K31/53; A61K31/5377; A61K31/55; A61K31/551; A61K45/00; A61P1/04; A61P3/10; A61P5/00; A61P9/00; A61P9/02; A61P9/08; A61P9/10; A61P11/00; A61P11/02; A61P11/06; A61P13/08; A61P13/10; A61P13/12; A61P15/00; A61P17/00; A61P17/04; A61P17/06; A61P17/10; A61P17/14; A61P17/16; A61P19/02; A61P19/06; A61P21/04; A61P25/00; A61P25/16; A61P25/28; A61P27/02; A61P27/06; A61P29/00; A61P31/18; A61P35/00; A61P35/02; A61P37/02; A61P37/04; A61P37/06; A61P37/08; A61P43/00; C07C259/10; C07D207/09; C07D207/14; C07D211/26; C07D211/58; C07D213/74; C07D213/78; C07D217/02; C07D217/04; C07D239/42; C07D241/04; C07D295/14; C07D295/155; C07D295/20; C07D295/22; C07D295/26; C07D307/68; C07D317/58; C07D401/04; C07D401/06; C07D401/12; C07D401/14; C07D403/04; C07D403/12; C07D405/12; C07D405/14; C07D409/12; C07D413/02; C07D413/04; C07D413/12; C07D471/10; C12Q1/48; (IPC1-7): C07D295/14; A61K31/451; A61K31/4545; A61K31/4709; A61K31/4725; A61K31/506; A61P35/00; C07D401/14; C07D403/04
Domestic Patent References:
| JPS5668669A | 1981-06-09 | |||
| JPS5890552A | 1983-05-30 | |||
| JPS476025A | ||||
| JPS476026A |
Foreign References:
| WO2001038322A1 | 2001-05-31 |
Attorney, Agent or Firm:
Heikichi Odashima