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Title:
A cell culture device and a cell culture method
Document Type and Number:
Japanese Patent JP5988962
Kind Code:
B2
Abstract:
A bioreactor (1) for the culture of cells (C) comprising a stack of carriers (7) for cell (C) adherence and liquid medium (M) distribution. The carriers (7) are stacked so as to define levels (6) between adjacent carriers (7) for the flow of the liquid medium (M). Adjacent levels (6) are fluidly interconnected via open spaces (2) so that the liquid medium (M) can flow from one level (6) to an adjacent level (6). The open spaces (2) between a first and an adjacent second level (6′) do not overlap with the one or more open spaces (2) between the second level (6′) and an adjacent third level (6″). One or more of the carriers may also include an area adapted to prevent cell adhesion or growth, thereby allowing for the viewing of cell growth on adjacent carriers from a vantage point external to the bioreactor. Related methods are also disclosed.

Inventors:
Karelangabo, Didier
Cardon, Julian
Castillo Gonzales, Jose Antonio
Application Number:
JP2013509561A
Publication Date:
September 07, 2016
Filing Date:
May 11, 2011
Export Citation:
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Assignee:
Pall Artelis BVBA
International Classes:
C12M1/00; C12M3/00
Domestic Patent References:
JP2005270055A
JP2008132126A
JP2009124977A
JP2004344016A
JP2009502165A
JP2003093041A
Foreign References:
WO1988000235A1
WO2009069962A1
WO2010042072A1
US5658797
US6562616
Attorney, Agent or Firm:
Nobuyuki Iida
Kazuhiko Iida