Title:
A chromophoric group / fluorescent substances originating in flower Echiuroidea, and those directions
Document Type and Number:
Japanese Patent JP6074162
Kind Code:
B2
Abstract:
Nucleic acid compositions encoding novel chromo/fluoroproteins and mutants thereof are provided. The subject proteins of interest are proteins that are colored and/or fluorescent, where this feature arises from the interaction of two or more residues of the protein. The subject proteins are further characterized in that they are either obtained from non-bioluminescent Cnidarian, e.g., Anthozoan, species or are obtained from non-Pennatulacean (sea pen) species. Specific proteins of interest include proteins obtained from the following specific Anthozoan species: Anemonia majano (NFP-1), Clavularia sp. (NFP-2), Zoanthus sp. (NFP-3 & NFP-4), Discosoma striata (NFP-5), Discosoma sp. “red” (NFP-6), Anemonia sulcata (NFP-7), Discosoma sp “green” (NFP-8), and Discosoma sp.“magenta” (NFP-9). Also of interest are proteins that are substantially similar to, or mutants of, the above specific proteins. Also provided are fragments of the nucleic acids and the peptides encoded thereby, as well as antibodies to the subject proteins and transgenic cells and organisms. The subject protein and nucleic acid compositions find use in a variety of different applications. Finally, kits for use in such applications, e.g., that include the subject nucleic acid compositions, are provided.
Inventors:
Rukiyanov Sergey Anatolyevich
Hradkov Arkadi Fidlovich
Lavis Yuri Alexandrovich
Mats Mikhail Vladimirovich
Terskiff Alexei
Hradkov Arkadi Fidlovich
Lavis Yuri Alexandrovich
Mats Mikhail Vladimirovich
Terskiff Alexei
Application Number:
JP2012122888A
Publication Date:
February 01, 2017
Filing Date:
May 30, 2012
Export Citation:
Assignee:
Takara Bio USA, Inc.
International Classes:
C12N15/09; C07K14/44; C07K16/20; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/02
Foreign References:
| WO2000034526A1 |
Other References:
Nat.Biotechnol.,Oct.1999,Vol.17,p.969-973
Nature,1995,Vol.373,p.663-664
PNAS,1994,Vol.91,p.12501-12504
Nature,1995,Vol.373,p.663-664
PNAS,1994,Vol.91,p.12501-12504
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto