Title:
ククルビチュリル誘導体をホスト分子として含む包接化合物およびこれを含む薬剤組成物
Document Type and Number:
Japanese Patent JP4347693
Kind Code:
B2
Abstract:
The present invention provides an inclusion compound having a cucurbituril derivative of the formula 1 as a host molecule and a metal complex of the formula 2 as a guest molecule. A pharmaceutical composition having an anticancer effect can be obtained by using the inclusion compound according to the present invention. The pharmaceutical composition can prevent effective components from being biologically degraded in vivo and can exhibit continuous drug effect for a long time just by a single dosage by controlling the release time of the platinum complex once it reaches target tumor cells.
Inventors:
Kim, kimoon
Jeon, Yang, Jin
Kim, Sue Yang
Ko, Yangho
Jeon, Yang, Jin
Kim, Sue Yang
Ko, Yangho
Application Number:
JP2003528825A
Publication Date:
October 21, 2009
Filing Date:
September 18, 2002
Export Citation:
Assignee:
Postec Foundation
International Classes:
A61K33/24; C07D487/04; A61K47/22; A61K47/48; A61P35/00; C07F1/12; C07F5/00; C07F15/00
Domestic Patent References:
| JP2001122877A | ||||
| JP3275617A | ||||
| JP61178998A | ||||
| JP7112994A |
Foreign References:
| WO1999061450A1 |
Other References:
Metal-Based Drugs,1997年,Vol.4, No.6,pp.305-306
Journal of Controlled Release,1996年,Vol.40,pp.251-260
Carbohydrate Research,1989年,Vol.192,pp.259-281
Journal of Controlled Release,1996年,Vol.40,pp.251-260
Carbohydrate Research,1989年,Vol.192,pp.259-281
Attorney, Agent or Firm:
Hatta International Patent Corporation