Title:
A combination thing and a method for bone transition or prevention of other bone diseases, and medical treatment
Document Type and Number:
Japanese Patent JP6034001
Kind Code:
B2
Abstract:
A suspension of erythrocytes encapsulating a bisphosphonate is provided along with a method for its use for the prevention and treatment of bone metastases and other bone marrow diseases. The suspension of erythrocytes encapsulating a bisphosphonate may also be provided in which the erythrocytes have undergone a chemical treatment with an agent such as BS3 so as to promote targeting of the bone marrow. The method for the prevention and treatment of bone metastases may be accomplished by administering to a patient in need thereof of a suspension of erythrocytes encapsulating a second-generation or a third-generation bisphosphonate.
Inventors:
Burger, vanessa
God Flynn, Yang
God Flynn, Yang
Application Number:
JP2010550176A
Publication Date:
November 30, 2016
Filing Date:
March 10, 2009
Export Citation:
Assignee:
Erytech Pharma
International Classes:
A61K47/46; A61K9/10; A61K9/50; A61K31/663; A61K31/675; A61K47/22; A61P19/08; A61P19/10; A61P35/00; A61P35/04
Domestic Patent References:
| JP115752A |
Foreign References:
| WO2008016172A1 |
Other References:
LUIGIA ROSSIほか、“Macrophage depletion induced by clodronate-loaded erythrocytes”、Journal of Drug Targeting、2005年、13巻2号、99~111頁
Attorney, Agent or Firm:
Shinjiro Ono
Yasushi Kobayashi
Shigeo Takeuchi
Osamu Yamamoto
Takashi Nakata
Yasushi Kobayashi
Shigeo Takeuchi
Osamu Yamamoto
Takashi Nakata
Previous Patent: The constituent containing a Sphingosine - 1-phosphoric acid (S1P) receptor modulator
Next Patent: JPS6034002
Next Patent: JPS6034002