Title:
トリアムシノロンアセトニドおよびヒアルロン酸を好ましく含有する眼局所治療用組成物
Document Type and Number:
Japanese Patent JP2007518804
Kind Code:
A
Abstract:
Compositions, and methods of using such compositions, useful for injection into the posterior segments of human or animal eyes are provided. Such compositions include small particles of a poorly soluble therapeutic agent that facilitates formation of concentrated regions of the therapeutic agent in the retinal pigmented epithelium of an eye. The particles are formed by combining a therapeutic agent with an ophthalmically acceptable polymer component. The particles have sizes less than about 3000 nanometers, and in some cases, less than about 200 nanometers. One example of a composition includes particles of triamcinolone acetonide and hyaluronic acid have a size less than about 3000 nanometers.
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Inventors:
Patrick M. Hughes
Orest Olejunic
Scott M Whitcup
James A. Burke
Orest Olejunic
Scott M Whitcup
James A. Burke
Application Number:
JP2006551181A
Publication Date:
July 12, 2007
Filing Date:
January 14, 2005
Export Citation:
Assignee:
ALLERGAN,INCORPORATED
International Classes:
A61K9/14; A61K9/00; A61K9/10; A61K31/00; A61K31/573; A61K47/36; A61P5/42; A61P27/02
Domestic Patent References:
| JP2005529879A | 2005-10-06 | |||
| JP2004528267A | 2004-09-16 | |||
| JP2000247871A | 2000-09-12 |
Foreign References:
| WO2002015878A1 | 2002-02-28 | |||
| WO2003089008A1 | 2003-10-30 | |||
| WO2002005815A1 | 2002-01-24 |
Attorney, Agent or Firm:
Kyousei Tamura
Yushiro Tsuboi
Nagatoshi Shinagawa
Yushiro Tsuboi
Nagatoshi Shinagawa