Title:
水に溶けにくい薬物の送込み用組成物および方法並びに治療方法
Document Type and Number:
Japanese Patent JP2005508354
Kind Code:
A
Abstract:
The present embodiment of the invention is generally directed to compositions comprising suspensions of poorly water-soluble compounds recrystallized in nanoparticulate sizes ranging from 0.1 to 5 μm. In addition, the embodiment of the invention is directed to methods for preparation and administration of these compositions to a patient for prevention and treatment of disease states. In particular, the embodiment of the invention is directed to compositions comprising suspensions of poorly water-soluble compounds, such as antimitotics and antibiotics, in nanoparticulates and methods of prevention and treatment of chronic disease states, such as cancer, by intraperitoneal and intravenous administration of such compositions.
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Inventors:
Jonas, Jeffrey M
Rajewski, Roger A.
Subramaniam, rose
Terra Nova, Katherine Fern
Rajewski, Roger A.
Subramaniam, rose
Terra Nova, Katherine Fern
Application Number:
JP2003535712A
Publication Date:
March 31, 2005
Filing Date:
October 15, 2002
Export Citation:
Assignee:
Kurititech Inc.
International Classes:
A61K9/00; A61K9/10; A61K9/14; A61K31/337; A61K31/407; A61K31/4745; A61K31/475; A61K31/704; A61K31/7048; A61K38/00; A61K47/04; A61P35/00; A61K9/16; (IPC1-7): A61K31/337; A61K9/10; A61K9/14; A61K31/407; A61K31/4745; A61K31/475; A61K31/704; A61K31/7048; A61K38/00; A61K47/04; A61P35/00
Attorney, Agent or Firm:
Warren G. Simor