Title:
ABCA-1を上昇させる化合物
Document Type and Number:
Japanese Patent JP2004515498
Kind Code:
A
Abstract:
The present invention provides compounds that elevate cellular expression of the ABCA-1 gene, promoting cholesterol efflux from cells and increasing HDL levels in the plasma of a mammal, in particular humans. The compounds are useful for treating coronary artery disease.
Inventors:
Campbell, Michael
Ibrahim, Prabhaen.
Zabrocchi, Jeff A.
Loan, richard
Ibrahim, Prabhaen.
Zabrocchi, Jeff A.
Loan, richard
Application Number:
JP2002547919A
Publication Date:
May 27, 2004
Filing Date:
December 06, 2001
Export Citation:
Assignee:
CV THERAPEUTICS, INC.
International Classes:
A61K31/085; A61K31/136; A61K31/16; A61K31/165; A61K31/167; A61K31/17; A61K31/18; A61K31/357; A61K31/435; A61K31/47; A61K31/472; A61K31/495; A61K31/505; A61K45/00; A61K31/506; A61K31/53; A61K45/06; A61P3/06; A61P9/00; A61P9/10; A61P43/00; C07C237/04; C07C237/06; C07C237/22; C07C237/40; C07C275/26; C07C311/20; C07C323/36; C07C323/40; C07C323/60; C07C327/42; C07C327/44; C07C327/48; C07C335/16; C07D215/38; C07D217/24; C07D239/48; C07D251/16; C07D251/22; C07D251/52; C07D319/08; C07D319/18; C07D401/12; C07D405/12; C07D409/12; C07D409/14; C07D413/12; C07D413/14; (IPC1-7): C07C237/40; A61K31/085; A61K31/136; A61K31/357; A61K31/47; A61K31/472; A61P3/06; A61P9/10; A61P43/00; C07D215/38; C07D217/24; C07D319/08; C07D319/18
Attorney, Agent or Firm:
Hidekazu Miyoshi
Yasuo Miyoshi
Yasuo Miyoshi