Title:
Compositions and Methods for Antibodies Targeting the EPO
Document Type and Number:
Japanese Patent JP6306605
Kind Code:
B2
Abstract:
The present invention relates to compositions and methods for the inhibition of EPO. The invention provides antibodies and antigen binding fragments thereof that bind to EPO and are able to inhibit EPO-dependent cell proliferation and/or EPO-dependent cell signaling.
Inventors:
Gauche, Joy
Rats, Mark Anthony
Tissot-Dagette, Katrin Ulrike
Sprawski, Igor
Logska, michael
Rats, Mark Anthony
Tissot-Dagette, Katrin Ulrike
Sprawski, Igor
Logska, michael
Application Number:
JP2015546561A
Publication Date:
April 04, 2018
Filing Date:
December 03, 2013
Export Citation:
Assignee:
Novartis Age
International Classes:
C07K16/24; A61K39/395; A61P27/02; C07K16/46; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12P21/08
Other References:
Journal of Immunoassay & Immunochemistry, 2008, Vol.29, pp.181-196
The New England Journal of Medicine, 2005, Vol.353, No.8, pp.782-792
Experimental Diabetes Research, 2012.01, Vol.2012, Article ID. 548732
The New England Journal of Medicine, 2005, Vol.353, No.8, pp.782-792
Experimental Diabetes Research, 2012.01, Vol.2012, Article ID. 548732
Attorney, Agent or Firm:
Hiroshi Kobayashi
Norio Omori
Emiko Nishizawa
Yasuhito Suzuki
Norio Omori
Emiko Nishizawa
Yasuhito Suzuki