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Title:
A constituent and a method for detecting the variation in JAK2 nucleic acid
Document Type and Number:
Japanese Patent JP6017136
Kind Code:
B2
Abstract:
The invention disclosed herein is based on the identification of novel mutations in the JAK2 gene and JAK2 protein. The invention provides compositions and methods useful for diagnosing hematopoietic diseases including, for example, myeloproliferative diseases. The invention also provides compositions and methods useful for determining a prognosis of an individual diagnosed as having a hematopoietic disease.

Inventors:
Albital, Maher
Ma, Won Long
Application Number:
JP2011534635A
Publication Date:
October 26, 2016
Filing Date:
October 22, 2009
Export Citation:
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Assignee:
Quest Diagnostics Investments Inc.
International Classes:
C12N15/09; C12N9/12; C12Q1/68; G01N33/53
Foreign References:
US20070248961
WO2007124309A1
Other References:
Clin.Cancer Res.(2008.October.1)Vol.14,No.19 Suppl.,p.B12(Abs.B12)
J.Mol.Diagn.(2009.Jan)Vol.11,No.1,p.49-53
Sus scrofa clone UMNp1381 microsatellite sequence.,[online],GenBank,2006年8月13日,Acc.No: DQ837774,[検索日]平成27年10月26日,URL,http://www.ncbi.nlm.nih.gov/nuccore/111378807/
Leuk.Lymphoma(2008.Mar.)Vol.49,No.3,p.388-397
Blood(2008.Apr.)Vol.111,No.7,p.3863-3866
N.Engl.J.Med.(2007)Vol.356,No.5,p.459-468
Hum.Pathol.(2008.Jun.)Vol.39,No.6,p.795-810
Attorney, Agent or Firm:
Seiji Ohno
Reiko Tanaka
Yuko Matsuniya