Title:
A constituent and a method for prevention of addiction, and medical treatment
Document Type and Number:
Japanese Patent JP6163289
Kind Code:
B2
Abstract:
The present invention relates to methods of treating or preventing addiction and relapse use of addictive agents, and treating or preventing addictive or compulsive behaviour and relapse practice of an addictive behaviour or compulsion, by administering a peroxisome proliferator-activated receptor gamma (PPAR) agonist, alone or in combination with another therapeutic agent, such as, for example, an opioid receptor antagonist or an antidepressant, or an addictive agent, such as, for example, an opioid agonist. The present invention also includes pharmaceutical compositions for treating or preventing addiction or relapse that include a PPAR agonist and one or more other therapeutic or addictive agents, as well as unit dosage forms of such pharmaceutical compositions, which contain a dosage effective in treating or preventing addiction or relapse. The methods and compositions of the invention are useful in the treatment or prevention of addiction to any agent, including alcohol, nicotine, marijuana, cocaine, and amphetamines, as well as compulsive and addictive behaviours, including pathological gambling and pathological overeating.
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Inventors:
Chicco Cipopo, Roberto
Application Number:
JP2011554216A
Publication Date:
July 12, 2017
Filing Date:
March 11, 2010
Export Citation:
Assignee:
Omelos Corporation
International Classes:
A61K31/427; A61K31/426; A61K31/4439; A61K31/485; A61P25/30; A61P43/00
Foreign References:
| WO2008128126A1 |
Other References:
J. Pharmacol. Exp. Ther., 1999, Vol.290, No.3, pp.1369-1374
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Kosemura Akiko
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Kosemura Akiko