Title:
A constituent and a method for re-programming a cell, without being accompanied by inheritable genetic modification, in order to restore cartilage damage
Document Type and Number:
Japanese Patent JP6113160
Kind Code:
B2
Abstract:
The present inventions are directed to compositions and methods regarding the reprogramming of other cells (such as embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), MSCs, fibroblasts, hematopoietic stem cells, endothelian stem cells, adipocytes, chondrocytes, osteoblasts, osteoclasts and endothelial cells) into chondrogenic cells without introducing exogenous genes to the samples. In particular, the present inventions are directed to transducible materials that are capable of transducing into the biological samples but are not genes or causing genetic modifications. The present inventions also are directed to methods of reprogramming the path of biological samples or treating diseases using the tranducible compositions thereof.
More Like This:
Inventors:
Zoo, yon
Woo, Siri
Bao, Jun
Chew, Conkey
Woo, Siri
Bao, Jun
Chew, Conkey
Application Number:
JP2014521809A
Publication Date:
April 12, 2017
Filing Date:
July 19, 2012
Export Citation:
Assignee:
Vivoscript, Incorporated
OREGON HEALTH & SCIENCE UNIVERSITY
OREGON HEALTH & SCIENCE UNIVERSITY
International Classes:
C12N15/09; A61K38/00; A61K48/00; C07K14/005; C07K14/195; C07K14/37; C07K14/435; C12N1/14; C12N1/18; C12N1/20; C12N5/0735; C12N5/077; C12N5/0775; C12N5/0789; C12N5/10
Foreign References:
| WO2010072406A1 | ||||
| WO2010071210A1 |
Other References:
Journal of Bone and Mineral Research,2009年,24, 5,826-836
Attorney, Agent or Firm:
Seiji Ohno
Keiko Kanemoto
Reiko Tanaka
Yuko Matsuniya
Ken Kitano
Natsuki Ito
Umeda Shinsuke
Keiko Kanemoto
Reiko Tanaka
Yuko Matsuniya
Ken Kitano
Natsuki Ito
Umeda Shinsuke
Previous Patent: The Epigenes tick marker which identifies a natural killer cell
Next Patent: BIOLOGICAL ANALYSER
Next Patent: BIOLOGICAL ANALYSER