Title:
虚血および虚血・再灌流障害を治療するための組成物および方法
Document Type and Number:
Japanese Patent JP2012526842
Kind Code:
A
Abstract:
and methods of using such compounds to activate cytoprotective kinases. The values and preferred values of the variables in Structural Formula I are defined herein.
Inventors:
Bagis, Alexander, Bee.
Bukes, Rainier
Kazare, Ralph
Kates, Stephen, A.
Ladder, Alan, Es.
Bukes, Rainier
Kazare, Ralph
Kates, Stephen, A.
Ladder, Alan, Es.
Application Number:
JP2012511009A
Publication Date:
November 01, 2012
Filing Date:
May 13, 2010
Export Citation:
Assignee:
Ischemix LLC
International Classes:
C07D339/04; A61K31/385; A61P9/10
Domestic Patent References:
| JP2003518477A | 2003-06-10 | |||
| JP2003518477A | 2003-06-10 |
Foreign References:
| WO2007027559A2 | 2007-03-08 | |||
| WO2006101909A2 | 2006-09-28 | |||
| WO2006101909A2 | 2006-09-28 | |||
| WO2007027559A2 | 2007-03-08 |
Other References:
JPN7013002176; ＳＴＮ Ｉｎｔｅｒｎａｔｉｏｎａｌ: 'Ｌ-Ａｌａｎｉｎｅ， Ｎ-［５-（３Ｒ）-１，２-ｄｉｔｈｉｏｌａｎ-３-ｙｌ-１-ｏｘｏｐｅｎｔｙｌ］-Ｌ-alpha-ｇｌｕｔａｍｙｌ-' ｆｉｌｅ ＲＥＧＩＳＴＲＹ ［ｏｎｌｉｎｅ］ ２００６年１０月１８日掲載, ［平成２５年６月６日検索］
JPN6014002895; Ｍａｎｊｕ Ｂａｌａ ｅｔ ａｌ: 'Ｎｏｖｅｌ ｐｅｐｔｉｄｏｍｉｍｉｃｓ ａｓ ａｎｇｉｏｔｅｎｓｉｎ-Ｃｏｎｖｅｒｔｉｎｇ ｅｎｚｙｍｅ ｉｎｈｉｂｉｔｏｒｓ： Ａ ｃｏｍｂｉｎａｔｏｒｉａｌ ａｐｐｒｏａｃｈ' Ｂｉｏｏｒｇａｎｉｃ ＆ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ Ｖｏｌ．１０， Ｎｏ．１１, 2002, ｐ．３６８５-３６９１
JPN6014002895; Ｍａｎｊｕ Ｂａｌａ ｅｔ ａｌ: 'Ｎｏｖｅｌ ｐｅｐｔｉｄｏｍｉｍｉｃｓ ａｓ ａｎｇｉｏｔｅｎｓｉｎ-Ｃｏｎｖｅｒｔｉｎｇ ｅｎｚｙｍｅ ｉｎｈｉｂｉｔｏｒｓ： Ａ ｃｏｍｂｉｎａｔｏｒｉａｌ ａｐｐｒｏａｃｈ' Ｂｉｏｏｒｇａｎｉｃ ＆ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ Ｖｏｌ．１０， Ｎｏ．１１, 2002, ｐ．３６８５-３６９１
Attorney, Agent or Firm:
Yoshinori Hosoda