CREATINE PRODRUGS, COMPOSITIONS AND METHODS OF USE THEREOF

Title:

CREATINE PRODRUGS, COMPOSITIONS AND METHODS OF USE THEREOF

Document Type and Number:

Japanese Patent JP2020128379

Kind Code:

A

Abstract:

To provide methods of treating diseases such as ischemia, heart failure, neurodegenerative disorders and genetic disorders affecting the creatine kinase system.SOLUTION: The invention describes membrane permeable creatine prodrugs, pharmaceutical compositions comprising membrane permeable creatine prodrugs, and treating methods including administering creatine prodrugs or pharmaceutical compositions thereof.SELECTED DRAWING: None

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Inventors:

WILLIAM F BRUBAKER

Application Number:

JP2020072408A

Publication Date:

August 27, 2020

Filing Date:

April 14, 2020

Export Citation:

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Assignee:

FARMINGTON PHARMA DEV

International Classes:

C07D271/06; A61K31/4245; A61K31/5395; A61P9/00; A61P9/10; A61P21/00; A61P25/00; A61P25/18; C07D273/04; C07D413/12

Foreign References:

WO2014018570A1	2014-01-30
WO2014019855A1	2014-02-06
WO2014097335A1	2014-06-26
WO2008101310A1	2008-08-28
WO2007146086A1	2007-12-21
WO2005108370A1	2005-11-17

Attorney, Agent or Firm:

Masaki Hirota
Seiji Ozawa
Yusaku Tokai
Makoto Horiuchi
Masako Yamauchi
Shuichi Sonomoto
Akihiro Yamamura
Hiroyuki Tomita

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