Title:
アスタキサンチンの結晶形
Document Type and Number:
Japanese Patent JP5597895
Kind Code:
B2
Abstract:
The invention describes previously undisclosed crystal forms of astaxanthin designated crystal form I and II. It has been surprisingly found that the two crystal forms of astaxanthin show an improved bioavailability, a relatively high solubility in specific organic solvents and an increased long-term stability. For example the new forms are stable in solid form for at least 90 days at a temperature of 20° C.-40° C. It was further found that the two crystal forms can be prepared from each other. Therefore the invention also relates to methods for preparing said crystal forms. In addition, the invention relates to administration forms (hereinafter also called “formulations”) comprising one of the two crystal forms according to the invention or mixtures thereof dissolved or suspended in oil or organic-solvent.
Inventors:
ゴウ and Jin Fay
Jones, Matthew, and Jay.
Shaffer and Christiane
Ulich and Joachim
ヴェルハク Trichet and Vivian
Jones, Matthew, and Jay.
Shaffer and Christiane
Ulich and Joachim
ヴェルハク Trichet and Vivian
Application Number:
JP2011511034A
Publication Date:
October 01, 2014
Filing Date:
June 02, 2009
Export Citation:
Assignee:
DSM IP アセッツ B. buoy.
International Classes:
C07C403/24; A01K61/00
Attorney, Agent or Firm:
Ikeda Adult
Kazuhiro Yamaguchi
Noda Masakazu
Yoshinori Shimizu
Kazuhiro Yamaguchi
Noda Masakazu
Yoshinori Shimizu