Title:
抗癌剤としてのアポゴシポロン誘導体
Document Type and Number:
Japanese Patent JP2013507380
Kind Code:
A
Abstract:
The disclosure provides compounds and methods of using Apogossypolone derivatives for treating diseases and disorders. In particular, the disclosure provides compounds of Formula I: or a pharmaceutically acceptable salt, hydrate, or solvate thereof, and provides methods for the preparation of compounds of Formula I; and methods for treating cancer, autoimmune diseases, and inflammation by administering a compound of Formula I.
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Inventors:
Perezcia, Maurizio
Way, Jun
Way, Jun
Application Number:
JP2012533321A
Publication Date:
March 04, 2013
Filing Date:
October 07, 2010
Export Citation:
Assignee:
Sanford-Burnham Medical Research Institute
International Classes:
C07C50/10; A61K31/122; A61K31/16; A61P1/00; A61P1/04; A61P3/10; A61P5/14; A61P7/06; A61P9/00; A61P11/00; A61P11/02; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P19/02; A61P21/04; A61P25/00; A61P25/28; A61P29/00; A61P35/00; A61P37/06; A61P43/00; C07C235/84
Domestic Patent References:
| JP2008531465A | 2008-08-14 |
Foreign References:
| US20090105319A1 | 2009-04-23 |
Other References:
JPN5013001652; ＡＲＮＯＬＤ: 'ＰＲＥＣＬＩＮＩＣＡＬ ＳＴＵＤＩＥＳ ＯＦ ＡＰＯＧＯＳＳＹＰＯＬＯＮＥ： Ａ ＮＥＷ ＮＯＮＰＥＰＴＩＤＩＣ ＰＡＮ ＳＭＡＬＬ-ＭＯＬＥＣＵＬＥ以下備考' ＭＯＬＥＣＵＬＡＲ ＣＡＮＣＥＲ Ｖ７ Ｎ２０, 2008, Ｐ１-１０
JPN6013057754; Ｊ． Ｍｅｄ． Ｃｈｅｍ． ５２, 2009, ４５１１-４５２３
JPN6013057754; Ｊ． Ｍｅｄ． Ｃｈｅｍ． ５２, 2009, ４５１１-４５２３
Attorney, Agent or Firm:
Kazuhiro Kiyohara