【発明の名称】シソミシン誘導体

Title:

【発明の名称】シソミシン誘導体

Document Type and Number:

Japanese Patent JPH0735394

Kind Code:

B2

Abstract:

A high yielding process for converting 3,2',6'-tri-N-acetyl sisomicin to netilmicin comprising the step of silylating the starting material at the 5,2" positions, and optionally at the 4" position, converting the 1-amino substituents to a 1-N-imino substituent, converting the imino to an ethylamino, deprotecting the compound and recovering netilmicin. Also disclosed are novel intermediate compounds.

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Inventors:

Tan, Butterfly-Hong
Surubenga Dam, Thiruvettipuram Kannapan
Chiu, John Shahan
Cologne, caesar

Application Number:

JP30904893A

Publication Date:

April 19, 1995

Filing Date:

December 09, 1993

Export Citation:

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Assignee:

SCHERING CORPORATION

International Classes:

C07H1/00; A61K31/70; A61K31/7028; A61K31/7034; A61K31/7036; A61K31/7135; A61P31/04; C07H15/236; C07H17/04; C07H23/00; C07H; (IPC1-7): C07H23/00; C07H15/236

Attorney, Agent or Firm:

Kyozo Yuasa (4 outside)

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