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Title:
A device for nucleic acid seeking Enshingu using tunnel current analysis
Document Type and Number:
Japanese Patent JP6033448
Kind Code:
B2
Abstract:
An assembly for nucleic acid sequencing by tunnel current analysis has at least two electrically conductive particles having a diameter from 1 nm to 100 nm and at least two electrically insulating particles having a diameter from 1 nm to 100 nm. The particles are in particular spherically shaped. The assembly also has at least two first electrodes for contacting the electrically conductive particles and a substrate on which the first electrodes and the particles are arranged. The four particles are arranged substantially in a planar square. The conductive particles lie diagonally opposite each other, and the insulating particles lie diagonally opposite each other. The gap between the four particles is used as a solid-state nanopore for nucleic acid sequencing.

Inventors:
Walter Gumbrecht
Oliver Heiden
Application Number:
JP2015533535A
Publication Date:
November 30, 2016
Filing Date:
September 18, 2013
Export Citation:
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Assignee:
Siemens Aktiengesellschaft
International Classes:
C12M1/34; C12M1/00
Domestic Patent References:
JP2011119071A
JP2006119140A
JP2010513853A
JP2004519248A
Foreign References:
WO2011096936A1
US20120193236
US20120193231
US20060019259
Other References:
ALBRECHT T. et al,ACS NANO,5(8)(2011),p.6714-6725
IVANOV A.P. et al,NANO Lett. ,11(2011),p.279-285
Attorney, Agent or Firm:
Einzel Felix-Reinhard
Takuya Kuno