Title:
A diaminopyrazine compound, a drug containing the compound, its use, and a method for preparing the diaminopyrazine compound.
Document Type and Number:
Japanese Patent JP6353032
Kind Code:
B2
Abstract:
The present invention relates to compounds of general formula (I) and the tautomers and the salts thereof, particularly the pharmaceutically acceptable salts thereof with inorganic or organic acids and bases, which have valuable pharmacological properties, particularly an inhibitory effect on epithelial sodium channels and the use thereof for the treatment of diseases, particularly diseases of the lungs and airways.
Inventors:
Heckel Armin
Creijerk
Creijerk
Application Number:
JP2016511017A
Publication Date:
July 04, 2018
Filing Date:
April 25, 2014
Export Citation:
Assignee:
Boehringer Ingelheim International GmbH
International Classes:
C07D401/14; A61K31/498; A61K31/517; A61K45/00; A61P1/18; A61P11/00; A61P11/02; A61P11/04; A61P11/06; A61P11/08; A61P11/16; A61P29/00; A61P31/00; A61P37/08; A61P43/00; C07D403/14; C07D409/14; C07D417/14; C07D471/04
Domestic Patent References:
| JP2010526118A | ||||
| JP2011506386A | ||||
| JP2007502830A |
Other References:
J. Med. Chem.,2006年,49,4098-4115
Attorney, Agent or Firm:
Takaki Nishijima
Disciple Maru Ken
Shinichiro Tanaka
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Yasushi Sasaki
Disciple Maru Ken
Shinichiro Tanaka
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Yasushi Sasaki
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