Title:
抗炎症剤としての6α,9α-ジフルオロ-17α-[(2-フラニルカルボキシル)オキシ]-11β-ヒドロキシ-16α-メチル-3-オキソ-アンドロスト-1,4-ジエン-17-チオカルボン酸S-フルオロメチルエステル
Document Type and Number:
Japanese Patent JP4436041
Kind Code:
B2
Abstract:
According to one aspect of the invention, there is provided a compound of formula (I)
and solvates thereof. There are also provided compositions containing the compound, processes for preparing it, and its use in therapy.
Inventors:
Biga dike, case
Coot, Stephen, John
Nice, Roslyn, Kay
Coot, Stephen, John
Nice, Roslyn, Kay
Application Number:
JP2002518238A
Publication Date:
March 24, 2010
Filing Date:
August 03, 2001
Export Citation:
Assignee:
GLAXO GROUP LIMITED
International Classes:
A61K9/12; C07J17/00; A61K9/14; A61K31/56; A61K31/58; A61K45/00; A61K47/06; A61K47/18; A61K47/36; A61P5/44; A61P11/06; A61P11/08; A61P29/00; A61P37/08; A61P43/00; C07J31/00; C07J33/00; C07J43/00
Domestic Patent References:
| JP56138200A | ||||
| JP57146800A | ||||
| JP11503352A | ||||
| JP3167120A | ||||
| JP2004505990A | ||||
| JP49080058A |
Foreign References:
| WO2000033892A1 |
Other References:
SHAPIRO E L,JOURNAL OF MEDICINAL CHEMISTRY,米国,AMERICAN CHEMICAL SOCIETY,1987年,V30N9,P1581-1588
PHILLIPPS G H,JOURNAL OF MEDICINAL CHEMISTRY,米国,AMERICAN CHEMICAL SOCIETY.,1994年10月 1日,V37N22,P3717-3729
SOUNESS, J. E.,Immunosuppressive and anti-inflammatory effects of cyclic AMP phosphodiesterase (PDE) type 4 inhibitors,Immunopharmacology,2000年,47(2/3),p. 127-162
POPPER T L,JOURNAL OF STEROID BIOCHEMISTRY,英国,PERGAMON PRESS PLC,1987年,V27N4-6,P837-843
PHILLIPPS G H,JOURNAL OF MEDICINAL CHEMISTRY,米国,AMERICAN CHEMICAL SOCIETY.,1994年10月 1日,V37N22,P3717-3729
SOUNESS, J. E.,Immunosuppressive and anti-inflammatory effects of cyclic AMP phosphodiesterase (PDE) type 4 inhibitors,Immunopharmacology,2000年,47(2/3),p. 127-162
POPPER T L,JOURNAL OF STEROID BIOCHEMISTRY,英国,PERGAMON PRESS PLC,1987年,V27N4-6,P837-843
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Ai Fujii
Satoshi Fujita
Ai Fujii