Title:
イソプレノイド化合物を生産するための遺伝的に修飾された宿主細胞および同宿主細胞の使用方法
Document Type and Number:
Japanese Patent JP5590769
Kind Code:
B2
Abstract:
The present invention provides genetically modified eukaryotic host cells that produce isoprenoid precursors or isoprenoid compounds. A subject genetically modified host cell comprises increased activity levels of one or more of mevalonate pathway enzymes, increased levels of prenyltransferase activity, and decreased levels of squalene synthase activity. Methods are provided for the production of an isoprenoid compound or an isoprenoid precursor in a subject genetically modified eukaryotic host cell. The methods generally involve culturing a subject genetically modified host cell under conditions that promote production of high levels of an isoprenoid or isoprenoid precursor compound.
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Inventors:
Key sling Jay Dee.
Paradise Eric M.
Kirby James
Paradise Eric M.
Kirby James
Application Number:
JP2007523676A
Publication Date:
September 17, 2014
Filing Date:
July 21, 2005
Export Citation:
Assignee:
ザリージェンツ オブ ザユニ bar city オブ California
International Classes:
C12N1/19; C12N15/09; C12P23/00
Attorney, Agent or Firm:
Spring water Original aim
Koichi Niimi
Koichi Niimi