Title:
the [for the disposal of asymptomatic brain ischaemia and the ischemia of other organs] -- XII factor inhibitor
Document Type and Number:
Japanese Patent JP6113668
Kind Code:
B2
Abstract:
Silent brain ischemia (SBI) or ischemia of other organs can result from an embolism that is introduced into the arterial system during a medical procedure. The application provides a method of administering a FXII inhibitor in a patient receiving a medical procedure and animal models useful for studying ischemia including SBI and ischemia in other organs, and for evaluating candidate therapeutics.
Inventors:
Matthias Narendorf
Ralph Weissleader
Gerhard Dick Knight
Guido Stall
Marc Norte
Ralph Weissleader
Gerhard Dick Knight
Guido Stall
Marc Norte
Application Number:
JP2013557117A
Publication Date:
April 12, 2017
Filing Date:
March 09, 2012
Export Citation:
Assignee:
TSE L Bering GMBH
The General Hospital Corporation
The General Hospital Corporation
International Classes:
A61K38/55; A61K39/395; A61K47/50; A61P7/02; A61P25/00
Domestic Patent References:
| JP2010518039A | ||||
| JP2008525342A |
Other References:
Circulation,2010年,121(13),1510-7
Neurosci Res.,2009年,65(1),71-8
Lancet,1999年,354,1594-7
haemostaseologie,2010年,30(1),A98,P15-11
血栓止血誌,2009年,20(6),602-7
基礎と臨床,1991年,25(9),2779-83
Neurosci Res.,2009年,65(1),71-8
Lancet,1999年,354,1594-7
haemostaseologie,2010年,30(1),A98,P15-11
血栓止血誌,2009年,20(6),602-7
基礎と臨床,1991年,25(9),2779-83
Attorney, Agent or Firm:
Junji Yuda
Noriyuki Takebayashi
Noriyuki Takebayashi
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