Title:
チエノ[2,3-c]ピリジン誘導体を含む薬剤組成物、及びその使用
Document Type and Number:
Japanese Patent JP2006516610
Kind Code:
A
Abstract:
The present invention provides thieno[2,3-C]pyridine derivatives, pharmaceutical compositions comprising the thieno[2,3-C]pyridine derivatives, and methods of use thereof. The compounds capable of inhibiting glycosaminoglycan (GAG) interactions with effector cell adhesion molecules (ECAM) are useful for treating diseases and disorders mediated by GAG-ECAMs interactions, particularly inflammatory and autoimmune diseases, viral diseases, cancer, and amyloid disorders.
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Inventors:
Gregger, Paul
Harris, Nicholas
Coppell, Yurai
Chuk, Regina
Harris, Nicholas
Coppell, Yurai
Chuk, Regina
Application Number:
JP2006502633A
Publication Date:
July 06, 2006
Filing Date:
February 05, 2004
Export Citation:
Assignee:
Limonix Pharmaceuticals Limited
International Classes:
C07D495/04; A61K31/4365; A61K31/496; A61K31/5355; A61K31/55; A61P1/00; A61P1/18; A61P3/10; A61P7/00; A61P7/02; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P17/00; A61P17/02; A61P17/06; A61P19/02; A61P25/00; A61P25/28; A61P27/02; A61P29/00; A61P31/04; A61P31/12; A61P31/18; A61P33/06; A61P35/00; A61P35/02; A61P35/04; A61P37/02; A61P43/00; C07D497/04
Domestic Patent References:
| JP2002517396A | 2002-06-18 | |||
| JP2001151780A | 2001-06-05 | |||
| JP2002517396A | 2002-06-18 | |||
| JP2001151780A | 2001-06-05 |
Foreign References:
| WO2000075145A1 | 2000-12-14 | |||
| WO2000075145A1 | 2000-12-14 |
Other References:
JPN6010027305, ＢＡＬＡＫＩＮ，Ｋ．Ｖ． ｅｔ ａｌ, "Ｐｒｏｐｅｒｔｙ−ｂａｓｅｄ ｄｅｓｉｇｎ ｏｆ ＧＰＣＲ−ｔａｒｇｅｔｅｄ ｌｉｂｒａｒｙ", Ｊｏｕｒｎａｌ ｏｆ Ｃｈｅｍｉｃａｌ Ｉｎｆｏｒｍａｔｉｏｎ ａｎｄ Ｃｏｍｐｕｔｅｒ Ｓｃｉｅｎｃｅｓ, 2002, Ｖｏｌ．４２， Ｎｏ．６, ｐｐ．１３３２−１３４２
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda