FIXED DOSE FORMULATIONS - Esperion Therapeutics, Inc.

Title:

FIXED DOSE FORMULATIONS

Document Type and Number:

Japanese Patent JP2023022224

Kind Code:

A

Abstract:

To provide stable and effective pharmaceutical compositions that allow formulation of bempedoic acid and ezetimibe that have improved, desirable pharmacokinetic and bulk physical properties.SOLUTION: A pharmaceutical composition comprises: bempedoic acid admixed with a lubricant selected from the group consisting of colloidal silicon dioxide, sodium stearyl fumarate, and magnesium stearate; ezetimibe; and a pharmaceutically acceptable excipient. The formulations herein provide pharmaceutical compositions having excellent stability and release properties for both drug products. These improved formulations are useful in the treatment and prevention of cardiovascular disease.SELECTED DRAWING: None

More Like This:

JP2019182818	INTRAORAL DISINTEGRABLE TABLET FOR REMOVING TONGUE COATING AND METHOD FOR REMOVING TONGUE COATING
JP2009286801	METHOD OF TREATING OR PREVENTING VASCULAR INFLAMMATION USING STEROL ABSORPTION INHIBITOR
WO/2009/152374	METHOD FOR TREATING CHRONIC WOUNDS WITH AN EXTRACELLULAR POLYMERIC SUBSTANCE SOLVATING SYSTEM

Inventors:

Abdernasale, Mohamed
Pirga on Cal, Plativa, Es.
Gandhi, Anilkumar S.

Application Number:

JP2022191728A

Publication Date:

February 14, 2023

Filing Date:

November 30, 2022

Export Citation:

Click for automatic bibliography generation Help

Assignee:

Esperion Therapeutics, Inc.

International Classes:

A61K31/194; A61K9/14; A61K9/16; A61K9/20; A61K9/24; A61K31/397; A61K47/04; A61K47/12; A61K47/14; A61K47/20; A61K47/26; A61K47/32; A61K47/36; A61K47/38; A61P3/06; A61P9/00; A61P43/00

Attorney, Agent or Firm:

Patent Attorney Corporation Hiraki International Patent Office

Previous Patent: fuel injector

Next Patent: RIP1 inhibitor compounds and methods for making and using same