A frizzled binding material and its use - Oncomed Pharmaceuticals Incorporated

Title:

A frizzled binding material and its use

Document Type and Number:

Japanese Patent JP6212070

Kind Code:

B2

Abstract:

Novel anti-cancer agents, including, but not limited to, antibodies, that bind to human frizzled receptors are provided. Novel epitopes within the human frizzled receptors which are suitable as targets for anti-cancer agents are also identified. Methods of using the agents or antibodies, such as methods of using the agents or antibodies to inhibit Wnt signaling and/or inhibit tumor growth are further provided.

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Inventors:

Gurney Austin Elle.
Sato Aaron Ken
Accelerator rod Fumiko Takada
Hoi Timothy Charles
Satyaru Sanjeeve H.
Mitra Sat Yasit Susit Kumar

Application Number:

JP2015100900A

Publication Date:

October 11, 2017

Filing Date:

May 18, 2015

Export Citation:

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Assignee:

Oncomed Pharmaceuticals Incorporated

International Classes:

C12N15/09; A61K31/337; A61K31/4745; A61K31/7068; A61K38/00; A61K39/395; A61K45/00; A61P35/00; A61P43/00; C07K16/28; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/08; C12Q1/06

Foreign References:

WO2007053577A1

Other References:

Biochem Biophys Res Comm,1998年,Vol.252, No.1,p.117-122

Attorney, Agent or Firm:

Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto

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