Title:
【発明の名称】複素環式ジオキセタン物質、その製造方法及びその使用
Document Type and Number:
Japanese Patent JPH11514359
Kind Code:
A
Abstract:
PCT No. PCT/EP96/04506 Sec. 371 Date Apr. 20, 1998 Sec. 102(e) Date Apr. 20, 1998 PCT Filed Oct. 17, 1996 PCT Pub. No. WO97/14696 PCT Pub. Date Apr. 24, 1997Compounds of the general formula Ia and Ib are described in which R1 and R2 are the same or different and represent hydrogen, straight-chain or branched C1 to C6 lower alkyl or an aryl group optionally substituted by electron-withdrawing groups, R3 denotes a cleavable group, W is hydrogen, halogen or a pseudohalogen and at least one of the groups R4 or R5 is a group stabilizing the dioxetane structure and at most one of the groups R4 or R5 represents hydrogen and X or Y represents oxygen, N-R or C(R)2 in which R has the meanings stated for R1 and R2 or represents a mesomeric double bond or a carbonyl group and n denotes the number 0 or 1 and m denotes the number 1 or 2, as well as a process for their production. These compounds are new and can be used as substrates in immunological assays and in DNA diagnostics using activating agents for colour formation.
More Like This:
Inventors:
Heidel, Dieter
Josel, Hans-Peter
Vonder Erz, Herbert
Hermann, Rupert
Holke, Hans-Youahim
Beckert, rainer
Wayth, Dieter
Adam, woldamar
Josel, Hans-Peter
Vonder Erz, Herbert
Hermann, Rupert
Holke, Hans-Youahim
Beckert, rainer
Wayth, Dieter
Adam, woldamar
Application Number:
JP51552897A
Publication Date:
December 07, 1999
Filing Date:
October 17, 1996
Export Citation:
Assignee:
Roche Diagnostics Gaem Behr
International Classes:
C07D321/00; C07D491/113; C07D493/10; C07F7/18; C07F9/38; C07F9/6561; C07J1/00; C07J17/00; C07J21/00; C07J51/00; G01N33/533; G01N33/58; (IPC1-7): C07D493/10; C07F7/18
Attorney, Agent or Firm:
Yusuke Hiraki (1 person outside)