Title:
複素環化合物
Document Type and Number:
Japanese Patent JP7282743
Kind Code:
B2
Abstract:
Provided is a compound that may have a superior CDK12 inhibitory action and is expected to be useful as a prophylactic or therapeutic drug for cancer and the like.A compound represented by the following formula (I):wherein each symbol is as described in the DESCRIPTION, or a salt thereof.
Inventors:
Koji Ono
Masahiro Ito
Toshio Tanaka
Souki Asano
Koji Hirayama
Jun Fujimoto
Nobutaka Sakauchi
Yasuhiro Hirata
Akinori Toida
Nao Morishita
Hironori Kokubo
Yasuhiro Imaeda
Hironobu Maezaki
Carrie Douglas Robert
Ryo Mizoshiri
Nobuo Cho
Hiroshi Sakano
Hidekazu Tokuhara
Yasuyoshi Arikawa
Masahiro Ito
Toshio Tanaka
Souki Asano
Koji Hirayama
Jun Fujimoto
Nobutaka Sakauchi
Yasuhiro Hirata
Akinori Toida
Nao Morishita
Hironori Kokubo
Yasuhiro Imaeda
Hironobu Maezaki
Carrie Douglas Robert
Ryo Mizoshiri
Nobuo Cho
Hiroshi Sakano
Hidekazu Tokuhara
Yasuyoshi Arikawa
Application Number:
JP2020509309A
Publication Date:
May 29, 2023
Filing Date:
March 28, 2019
Export Citation:
Assignee:
Takeda GmbH
International Classes:
C07D213/74; A61K31/44; A61K31/4433; A61K31/4436; A61K31/4439; A61K31/444; A61K31/4545; A61K31/496; A61K31/497; A61K31/501; A61K31/506; A61K31/513; A61K31/517; A61K31/5377; A61K31/5383; A61K31/5386; A61K31/541; A61K31/55; A61K31/551; A61K31/553; A61K31/554; A61P35/00; A61P43/00; C07D213/85; C07D401/12; C07D401/14; C07D403/12; C07D403/14; C07D405/12; C07D405/14; C07D409/12; C07D409/14; C07D413/12; C07D413/14; C07D417/12; C07D417/14; C07D451/06; C07D471/04; C07D471/10; C07D487/04; C07D487/10; C07D491/107; C07D493/08; C07D495/10; C07D498/04; C07D498/10; C07D513/04
Domestic Patent References:
| JP2016533379A |
Foreign References:
| WO2016142855A2 | ||||
| WO2016193939A1 | ||||
| EP1464335A2 |
Other References:
ITO, M. et al.,J. Med. Chem.,2018年08月01日,61(17),pp.7710-7728
FILE REGISTRY ON STN, RN 1026426-87-8, Entered STN: 08 Jun 2008
FILE REGISTRY ON STN, RN 1348645-64-6, Entered STN: 04 Dec 2011
FILE REGISTRY ON STN, RN 1026426-87-8, Entered STN: 08 Jun 2008
FILE REGISTRY ON STN, RN 1348645-64-6, Entered STN: 04 Dec 2011
Attorney, Agent or Firm:
Hajime Takashima
Mitsuyoshi Kamada
Kyoko Doi
Yaeko Tamura
Hirofumi Taima
Atsuko Akai
Tomiya Tosaki
Eiji Tabuse
Mitsuyoshi Kamada
Kyoko Doi
Yaeko Tamura
Hirofumi Taima
Atsuko Akai
Tomiya Tosaki
Eiji Tabuse
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