Title:
The heterocyclyl pyrimidine analogue as TYK2 inhibitor
Document Type and Number:
Japanese Patent JP6197031
Kind Code:
B2
Abstract:
The present invention relates to compounds of formula (I) wherein R, R1, X1 to X5 have the meaning as cited in the description and the claims. Said compounds are useful as TYK2 inhibitors for the treatment or prophylaxis of immunological, inflammatory, autoimmune, allergic disorders, and immunologically-mediated diseases. The invention also relates to pharmaceutical compositions including said compounds as well as their use as medicaments.
Inventors:
Richard, John, Harrison
Nigel, Ramsden
Jeremy, Major
Aderin, Morel
Laura, Conbury
Shunase beauty Yu
Rosemary, lynch
Rita, Adrego
Allison, Jones
Nigel, Ramsden
Jeremy, Major
Aderin, Morel
Laura, Conbury
Shunase beauty Yu
Rosemary, lynch
Rita, Adrego
Allison, Jones
Application Number:
JP2015513170A
Publication Date:
September 13, 2017
Filing Date:
May 23, 2013
Export Citation:
Assignee:
Cellsome Limited
International Classes:
C07D403/12; A61K31/506; A61K31/5377; A61P29/00; A61P37/04; A61P37/08; A61P43/00; C07D403/14; C07D405/14; C07D413/14; C07D417/14; C07D471/08; C07D487/10; C07D491/048; C07D491/107
Domestic Patent References:
| JP2014500254A |
Foreign References:
| WO2008132502A1 |
Attorney, Agent or Firm:
Hiroyuki Nagai
Yukitaka Nakamura
Yasukazu Sato
Satoru Asakura
Hirohito Katsunuma
Hiroshi Sorimachi
Hirosuke Endo
Yukitaka Nakamura
Yasukazu Sato
Satoru Asakura
Hirohito Katsunuma
Hiroshi Sorimachi
Hirosuke Endo
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