Title:
HYALURONIC ACID DERIVATIVE MODIFIED BY AMINO-CARBOXYLIC ACID
Document Type and Number:
Japanese Patent JP2017179374
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a hyaluronic acid derivative having both characteristics of biodegradability and blood retentivity and/or a hyaluronic acid derivative capable of delivering genes and medicines into a cytoplasm.SOLUTION: There is provided a hyaluronic acid derivative modified by a compound (amino-carboxylic acid) having alkylamine represented by the formula (I), amino such as amino acid and carboxy or the amide compound thereof (amino-carboxylic acid amide). There are provided a conjugate by binding the hyaluronic acid derivative and a medicine, a pharmaceutical composition containing the hyaluronic acid derivative, a composite of the hyaluronic acid derivative and the medicine.SELECTED DRAWING: None
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Inventors:
YASUGI TOMOKO
TANPO YOSHIHIRO
YASUGI KENJI
HIRAKURA YASUSHI
SHIMOFUSACHI TAKESHI
TANPO YOSHIHIRO
YASUGI KENJI
HIRAKURA YASUSHI
SHIMOFUSACHI TAKESHI
Application Number:
JP2017091352A
Publication Date:
October 05, 2017
Filing Date:
May 01, 2017
Export Citation:
Assignee:
CHUGAI PHARMACEUTICAL CO LTD
International Classes:
C08B37/08; A61K31/7088; A61K31/7105; A61K31/713; A61K38/18; A61K38/20; A61K38/21; A61K38/22; A61K38/27; A61K38/28; A61K38/30; A61K39/395; A61K47/36; A61K47/61
Domestic Patent References:
| JP2003518167A | 2003-06-03 | |||
| JPH03502704A | 1991-06-20 | |||
| JP2010524979A | 2010-07-22 |
Foreign References:
| WO2010053140A1 | 2010-05-14 |
Attorney, Agent or Firm:
Shinjiro Ono
Osamu Yamamoto
Toru Miyamae
Motoharu Nakanishi
Takumi Terachi
Osamu Yamamoto
Toru Miyamae
Motoharu Nakanishi
Takumi Terachi
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