Title:
非ステロイド系抗炎症薬の硫化水素誘導体
Document Type and Number:
Japanese Patent JP2009543813
Kind Code:
A
Abstract:
Derivatives of drugs are provided, said derivatives comprising the H2S-releasing moiety 4-hydroxythiobenzamide that is either covalently linked to the drug or forms a salt with the drug. The compounds of the present invention exhibit enhanced activity or reduced side effects or both.
Inventors:
Wallace, John, Elle.
Sirino, Giuzeppe
Santagada, Vinsenzo
Cariendo, Giuzeppe
Sirino, Giuzeppe
Santagada, Vinsenzo
Cariendo, Giuzeppe
Application Number:
JP2009519769A
Publication Date:
December 10, 2009
Filing Date:
July 18, 2007
Export Citation:
Assignee:
Antive Therapeutics Ink.
International Classes:
C07C327/48; A61K31/216; A61K31/26; A61K31/385; A61K31/404; A61P29/00; C07C331/28; C07D209/26; C07D339/04; C07D409/12
Domestic Patent References:
| JP2009543811A | 2009-12-10 | |||
| JP2008542209A | 2008-11-27 | |||
| JP2002541233A | 2002-12-03 |
Foreign References:
| WO2006037623A2 | 2006-04-13 | |||
| EP1645288A1 | 2006-04-12 | |||
| EP1630164A1 | 2006-03-01 |
Attorney, Agent or Firm:
Taro Yaguchi
Yoshiyuki Sasaki
Kazuya Sekiguchi
Yoshiyuki Sasaki
Kazuya Sekiguchi