Title:
疎水性素材に亜硝酸塩又は固形状酸性試薬を含浸させることにより、検体の展開を制御し得る、糖鎖抗原を抽出し測定するためのイムノクロマト試験片
Document Type and Number:
Japanese Patent JP7250539
Kind Code:
B2
Abstract:
The present invention has an object of providing: an immunochromatographic test strip, which controls the development of a specimen on the immunochromatographic test strip and appropriately controls a treatment with an acid reagent and a nitrite, and a neutralizing reagent; and an immunochromatography method using the test strip. The immunochromatographic test strip for extracting and measuring a sugar chain antigen in a specimen, comprising:a sample pad to which the specimen mixed with a nitrite or an acid solution is added;a label region comprising a labeled antibody obtained by labeling an antibody against the sugar chain antigen; and a detection region on which an antibody against the sugar chain antigen is immobilized,wherein an antibody-sugar chain antigen-labeled antibody complex is formed in the detection region to measure the sugar chain antigen, and wherein the immunochromatographic test strip has a region impregnated with a neutralizing reagent upstream of the label region, and further has, upstream of the region impregnated with the neutralizing reagent, a region impregnated with a solid acid reagent when the specimen mixed with the nitrite is used, or a region impregnated with the nitrite when the specimen mixed with the acid solution is used,wherein a hydrophobic material is used for the region impregnated with the nitrite or the solid acid reagent.
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Inventors:
Daisuke Kato
Muramatsu Shino
Muramatsu Shino
Application Number:
JP2019012974A
Publication Date:
April 03, 2023
Filing Date:
January 29, 2019
Export Citation:
Assignee:
Denka Co., Ltd.
International Classes:
G01N33/543; G01N33/53; G01N33/569
Domestic Patent References:
| JP2018151330A | ||||
| JP2018151331A | ||||
| JP2018151329A | ||||
| JP2014232064A |
Attorney, Agent or Firm:
Patent Attorney Corporation Hiraki International Patent Office