Title:
インドキサカルブの大規模化可能な調製方法
Document Type and Number:
Japanese Patent JP6746802
Kind Code:
B2
Abstract:
It is an object of the present invention to provide a novel and advantageous process for commercially preparing of indoxacarb which is racemic or enantiomerically enriched at chiral center from its amide precursor using a new catalytic system. More particularly, it relates to an efficient method of preparation of indoxacarb which is racemic or enantiomerically enriched at chiral center from methyl-7-chloro-2,5-dihydro-2-[[[(4-trifluoromethoxy) phenyl]amino]carbonyl]-indeno[1,2-e][1,3,4]oxadiazine-4a(3H) carboxylate represented as formula (I) using methoxycarbonylation agent and metal salt of methylsulfinylmethylide in hydrocarbon solvent in the presence of organic base and phase transfer catalyst.
Inventors:
Ben Kataramana, Rajuli
Vichidi, Jayapar Lady
Pilai, Bijukumar Gopinasan
Mannum, Three Devi
Vichidi, Jayapar Lady
Pilai, Bijukumar Gopinasan
Mannum, Three Devi
Application Number:
JP2019553295A
Publication Date:
August 26, 2020
Filing Date:
March 27, 2018
Export Citation:
Assignee:
Adama Makthesim Limited
International Classes:
C07D273/04; B01J31/02
Domestic Patent References:
| JP2013253170A |
Foreign References:
| US4065496 |
Other References:
GHARDA CHEMICALS LTD.,IN 2005MU00530 A,2005年11月14日
CHEMINOVA INDIA LTD,IN 2013MU00140 A,2014年10月17日
CHEMINOVA INDIA LTD,IN 2013MU00140 A,2014年10月17日
Attorney, Agent or Firm:
Makoto Onda
Hironobu Onda
Atsushi Honda
Miki Nakamura
Hironobu Onda
Atsushi Honda
Miki Nakamura