Title:
β―ラクタマーゼ耐性セファロスポリンエステル化合物とその塩
Document Type and Number:
Japanese Patent JP2007512261
Kind Code:
A
Abstract:
The present invention discloses the ²-lactamase resistant cephalosporin ester compounds represented by the following formula (I), characterized in that the structures of the compounds are composed by connecting methyl ester residue of sulbactam halomethyl ester with carboxyl residue of semi-synthetic cephalosporins or salts of thereof. The present invention also provides the pharmaceutical salts of thereof, and the use of thereof in preparation of oral antibiotics.
Inventors:
Feng Kou
Hozen
Lu Shui
Hozen
Lu Shui
Application Number:
JP2006540140A
Publication Date:
May 17, 2007
Filing Date:
November 19, 2004
Export Citation:
Assignee:
Zhejiang Yongning Pharmaceutical Factory
International Classes:
C07D519/06; A61K31/43; A61K31/546; A61P31/04; C07D501/00; C07D519/00
Domestic Patent References:
| JPS55157589A | 1980-12-08 | |||
| JPS58128387A | 1983-07-30 | |||
| JPS5325594A | 1978-03-09 | |||
| JPS52102295A | 1977-08-27 | |||
| JPS5780387A | 1982-05-19 | |||
| JPH0383988A | 1991-04-09 |
Foreign References:
| GB2094304A | 1982-09-15 | |||
| US4380512A | 1983-04-19 |
Attorney, Agent or Firm:
Yuzo Yamazaki
Naoto Sugiyama
Shirogane Expo
Toshiaki Akamatsu
Okuko Masako
Ichiro Tasaka
Takako Hoshi
Ono Wataru
Naoto Sugiyama
Shirogane Expo
Toshiaki Akamatsu
Okuko Masako
Ichiro Tasaka
Takako Hoshi
Ono Wataru