Title:
【発明の名称】17β―カルボキシ、カルボチオおよびアミドアンドロスタン誘導体のラクトン誘導体
Document Type and Number:
Japanese Patent JPH11501675
Kind Code:
A
Abstract:
Compounds of the androstane series are described having general formulaand solvates thereof, in which R1 represents O, S or NH; R2 individually represents OC(=O)C1-6 alkyl; R3 individually represents hydrogen, methyl (which may be in either the alpha or beta configuration) or methylene; or R2 and R3 together representwhere R6 and R7 are the same or different and each represents hydrogen or C1-6 alkyl; R4 and R5 are the same or different and each represents hydrogen or halogen and represents a single or a double bond. These compounds and their solvates have use in medicine as anti-inflammatory or anti-allergic agents.
Inventors:
Keith, Bigga Dyke
Panayotis, Alexandrou, Procorpio
Panayotis, Alexandrou, Procorpio
Application Number:
JP52409597A
Publication Date:
February 09, 1999
Filing Date:
December 19, 1996
Export Citation:
Assignee:
GLAXO GROUP LTD.
International Classes:
A61K31/00; A61P29/00; A61P37/08; C07J3/00; C07J17/00; A61K31/56; C07J31/00; C07J41/00; (IPC1-7): C07J3/00; A61K31/56; C07J17/00; C07J31/00; C07J41/00
Attorney, Agent or Firm:
Kazuo Sato (2 outside)
Previous Patent: 炎症治療用の１７β―（２―オキソテトラヒドロフラン―４―イル）チオ...
Next Patent: ２１―（２―オキソテトラヒドロフラン）チオプレグナン誘導体、それら...
Next Patent: ２１―（２―オキソテトラヒドロフラン）チオプレグナン誘導体、それら...