A light dynamic treatment about the state of an eye

Title:

A light dynamic treatment about the state of an eye

Document Type and Number:

Japanese Patent JP5988584

Kind Code:

B2

Abstract:

The use of a combination of photodynamic therapy and an anti-VEGF agent in the treatment of conditions characterized by unwanted choroidal neovasculature is described. These conditions include wet age-related macular degeneration Preferred anti-VEGF agents are antibodies such as bevacizumab or ranibizumab Photosensitizers may be selected from green porphyrins such as BPD-MA (verteporfin) and the photodynamic activation of the photo sensitizer may be accomplished using a reduced fluence rate. The use may further comprises an anti-inflammatory agent such as dexamethasone.

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Inventors:

Strong, H. Andrew
Hao, Yong

Application Number:

JP2011541048A

Publication Date:

September 07, 2016

Filing Date:

December 16, 2009

Export Citation:

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Assignee:

QLT Inc.

International Classes:

A61K45/06; A61K31/409; A61K31/573; A61K39/395; A61K41/00; A61P9/00; A61P27/02; A61P29/00; A61P43/00

Foreign References:

WO2007038453A2
WO2004080284A2
WO2002062385A2

Other References:

United States Clinical Trial, NCT00359164, (2008 Aug)(http://clinicaltrials.gov/archive/NCT00359164/2008_08_13)
United States Clinical Trial, NCT00492284, (2008 June)(http://clinicaltrials.gov/archive/NCT00492284/2008_06_02)
QLT NEWS RELEASE, QLT Completes Enrollment in the RADICAL Study. (2008 May)(http://www.qltinc.com/newsCenter/2008/documents/080505.pdf)
QLT NEWS RELEASE, Positive Results from Visudyne Combination Therapy Study Reported at Annual Macula Society Conference. (2008 March)(http://www.qltinc.com/newsCenter/2008/documents/080328.pdf)
Drugs Aging., Vol.24 No.12 p.979-90. (2007)
Invest Ophthalmol Vis Sci., Vol.48 No.4 p.1767-72. (2007)

Attorney, Agent or Firm:

Kato Asamichi
Kiuchi Uchida
Mitsuru Aoki

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