Title:
液体ナロキソンスプレー
Document Type and Number:
Japanese Patent JP7455157
Kind Code:
B2
Abstract:
The invention provides stable liquid formulations containing naloxone, a pharmaceutically acceptable salt, or a derivative thereof. The invention further provides methods for treating opioid dependence, opioid overdose, and congenital insensitivity to pain with anhidrosis by administering the liquid formulations of the present invention intranasally to a patient in need thereof. Further, the invention provides a method of treating opioid dependence-, opioid overdose, and congenital insensitivity to pain with anhidrosis by administering intranasally the naloxone formulations of the present invention.
Inventors:
Kiran Amancha
Shivani Chiramparri
Timothy Potter
Ninshin Yen
Benkat Earl Gosconda
Eshwaran Narayanan
Shivani Chiramparri
Timothy Potter
Ninshin Yen
Benkat Earl Gosconda
Eshwaran Narayanan
Application Number:
JP2022081328A
Publication Date:
March 25, 2024
Filing Date:
May 18, 2022
Export Citation:
Assignee:
Hikuma Pharmaceuticals U.S.A.Incorporated
International Classes:
A61K31/485; A61K9/12; A61K47/10; A61K47/18; A61K47/22; A61P25/00; A61P25/36; A61P39/02
Domestic Patent References:
| JP2019528278A | ||||
| JP2014513683A |
Foreign References:
| WO2016007245A1 | ||||
| WO2015038327A1 | ||||
| WO2015136373A1 | ||||
| CN1575795A |
Attorney, Agent or Firm:
Kawaguchi International Patent Office
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