Title:
病態治療のためのＲＮＡエディターのｍＲＮＡ駆動型発現
Document Type and Number:
Japanese Patent JP7399876
Kind Code:
B2
Abstract:
Compositions and methods for treating or inactivating viruses in a subject in need thereof are provided herein. Exemplary compositions include nucleic acids encoding an RNA-guided endonuclease and a guide RNA that is complementary to a target sequence in a virus. The RNA-guided endonuclease specifically targets viral nucleic acid sequences for destruction and suppression of that virus in a host cell in vitro or in vivo.
Inventors:
Bawaje Swapnil
Tiwari Pooja M.
Santangelo Philip Jay.
Tiwari Pooja M.
Santangelo Philip Jay.
Application Number:
JP2020557252A
Publication Date:
December 18, 2023
Filing Date:
April 15, 2019
Export Citation:
Assignee:
Georgia Tech Research Corporation
International Classes:
A61K38/46; A61K31/7105; A61K48/00; A61P31/14; A61P31/16; C12N15/09; C12N15/11; C12N15/55
Domestic Patent References:
| JP2017518372A |
Foreign References:
| WO2017219027A1 | ||||
| WO2017066588A2 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Hirotaka Yamaguchi
Shun Jinbe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Kazuya Kawamoto
Hirotaka Yamaguchi
Shun Jinbe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Kazuya Kawamoto
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