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Patent Searching and Data


Title:
Macrocyclic molecule useful for the treatment of Alzheimer's disease
Document Type and Number:
Japanese Patent JP2004534064
Kind Code:
A
Abstract:
The present invention are macrocycles of the formula (IX): for treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.

Inventors:
Pulley, shon, are
Beck, James, Pea
Ten Brink, Le Sui-
Application Number:
JP2003503623A
Publication Date:
November 11, 2004
Filing Date:
June 12, 2002
Export Citation:
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Assignee:
PHARMACIA & UPJOHN COMPANY
International Classes:
A61K31/395; A61K31/4427; A61P25/28; C07D273/02; C07D413/12; (IPC1-7): C07D273/02; A61K31/395; A61K31/4427; A61P25/28; C07D413/12
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda