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Patent Searching and Data


Title:
アルツハイマー病の治療に有用な大環状分子
Document Type and Number:
Japanese Patent JP2005505506
Kind Code:
A
Abstract:
The present invention is macrocycles of the formula (X): for treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme for the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.

Inventors:
Pulley, shon, are
Beck, James, Pea
Templink, loose, a-
Jacobs, John, S
Application Number:
JP2003503220A
Publication Date:
February 24, 2005
Filing Date:
June 12, 2002
Export Citation:
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Assignee:
PHARMACIA & UPJOHN COMPANY
Pharmacia and Upjohn Company Limited Liability Company
International Classes:
C07D291/02; A61K31/395; A61K31/407; A61K31/422; A61K31/4427; A61K31/4439; A61P9/00; A61P25/28; A61P43/00; C07D273/02; C07D413/04; C07D413/12; C07D413/14; C07D419/12; C07D498/08; (IPC1-7): C07D273/02; A61K31/395; A61K31/407; A61K31/422; A61K31/4427; A61K31/4439; A61P9/00; A61P25/28; A61P43/00; C07D291/02; C07D413/04; C07D413/12; C07D413/14; C07D419/12; C07D498/08
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda